Allergic orchitis lesions are adoptively transferred from vasoligated guinea pigs to syngeneic recipients

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Science  01 Sep 1978:
Vol. 201, Issue 4358, pp. 833-835
DOI: 10.1126/science.684410


Histopathology typical of allergic orchitis developed in testes of inbred guinea pigs 16 months after vasoligation. A similar histopathology was found in unoperated testes after unilateral vasoligation. Peritoneal exudate cells from vasoligated guinea pigs transferred identical lesions to syngeneic recipients. The testicular lesions in long-term vasoligated guinea pigs have an immunological basis.