Prolactin synthesis by human chorion-decidual tissue: a possible source of prolactin in the amniotic fluid

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Science  20 Oct 1978:
Vol. 202, Issue 4365, pp. 311-313
DOI: 10.1126/science.694535


Explants of human chorion-decidual tissue obtained at delivery from normal, full-term pregnancies synthesize and secrete prolactin. This hormone is indistinguishable from pituitary prolactin by chromatographic, electrophoretic, immunologic, and receptor assay techniques. These results suggest that chorion-decidua may be the source of the large quantities of prolactin in amniotic fluid.