Temperature Sensitivity: A Cell Character Determined by Obligate Endosymbionts in Amoebas

See allHide authors and affiliations

Science  10 Nov 1978:
Vol. 202, Issue 4368, pp. 635-637
DOI: 10.1126/science.202.4368.635


A strain of Amoeba proteus has lost its ability to survive at temperatures above 26°C as a result of becoming dependent on endosymbiotic bacteria that are psychrophile-like. The observed temperature sensitivity develops in fewer than 200 host cell generations (18 months of culture) after the host cells are experimentally infected with the symbionts.