Intracellular calcium: its release from granules during bursting activity in snail neurons

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Science  15 Dec 1978:
Vol. 202, Issue 4373, pp. 1195-1197
DOI: 10.1126/science.725594


Pentylenetetrazole induces a bursting activity accompanied by intracellular movement of calcium toward the cell membrane in the snail neuron. The calcium appears to originate from the dense lysosome-like granules in the cytoplasm. Pentylenetetrazole markedly depletes the granules of calcium and alters them ultrastructurally from dense granules to lamella type granules.