Membrane glycolipids: regional synthesis and axonal transport in a single identified neuron of Aplysia californica

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Science  05 Jan 1979:
Vol. 203, Issue 4375, pp. 78-80
DOI: 10.1126/science.83001


Glycolipids moving along an identified axon Aplysia californica were synthesized and incorporated into intracytoplasmic membranes solely in the perikaryon: direct injection of tritiated sugar into the axon revealed no local synthesis or exchange. There was no indication for transfer into axoplasm from glia. Insertion of glycolipids into nascent membranes occurs coordinately with insertion of protein components in the cell body.