Chemotactic factor-induced release of membrane calcium in rabbit neutrophils

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Science  02 Feb 1979:
Vol. 203, Issue 4379, pp. 461-463
DOI: 10.1126/science.760200


The interaction of chemotactic factors (fMet-Leu-Phe and C5a) with rabbit neutrophils leads to rapid and specific release of membrane calcium, as evidenced by changes in the fluorescence of cell-associated chlorotetracycline. These two structurally different stimuli appear to interact with the same pool of membrane calcium.