Reports

Prolonged inhibition of neurons by neuroendocrine cells in Aplysia

Science  27 Apr 1979:
Vol. 204, Issue 4391, pp. 417-420
DOI: 10.1126/science.35827

Abstract

In the abdominal ganglion of Aplysia, a burst of action potentials in peptide-secreting neuroendocrine cells, the bag cells, produces slow inhibition of two identified bursting pacemaker neurons. The inhibition is due to slow hyperpolarizing potential that reduces bursting pacemaker activity for 3 hours or more. The slow inhibitory potential results from a large and prolonged increase in membrane conductance to potassium ions as well as a slower ionic process that is relatively independent of membrane conductance.

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