Teleostean urophysis: urotensin II and ion transport across the isolated skin of a marine teleost

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Science  04 May 1979:
Vol. 204, Issue 4392, pp. 519-521
DOI: 10.1126/science.432657


The caudal neurosecretory peptide urotensin II rapidly inhibits by 30 percent the short-circuit current across the isolated skin of a marine teleost. The effect appears to be specific and cannot be attributed to actions of epinephrine, urotensin I, or arginine vasotocin. The results strongly suggest that urotensin II may act directly on ion-transporting cells involved in teleostean hypoosmoregulation.