Reports

Tissue perfusion rate determined from the decay of oxygen-15 activity after photon activation in situ

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Science  15 Jun 1979:
Vol. 204, Issue 4398, pp. 1215-1217
DOI: 10.1126/science.451567

Abstract

Rates of cerebral perfusion were obtained from measurements of the disappearance (wash-out) of oxygen-15 after in situ tissue activation with 45-million-volt x-rays. In an anesthetized cat, typical values were 90 milliliters per minute per 100 grams of tissue, with 55 percent wash-out. In a specific radiotherapy patient, the value was 65 milliliters per minute per 100 grams of tissue, with 63 percent wash-out of oxygen-15 through incorporation into tissue water.

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