The central origin of efferent pathways in the carotid sinus nerve of the cat

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Science  07 Sep 1979:
Vol. 205, Issue 4410, pp. 1017-1018
DOI: 10.1126/science.472721


The application of horseradish peroxidase to the central cut end of the carotid sinus nerve of the cat produced retrograde labeling of neurons in the ipsilateral medulla in the region of the nucleus ambiguus at anterior-posterior coordinates -8 to -10.5. These data coupled with previous electrophysiological observations suggest that the nucleus ambiguus may be the origin of an efferent inhibitory pathway to the carotid body.