Generation of unidirectionally propagated action potentials in a peripheral nerve by brief stimuli

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Science  14 Dec 1979:
Vol. 206, Issue 4424, pp. 1311-1312
DOI: 10.1126/science.515733


Single, unidirectionally propagated action potentials can be elicited in peripheral nerves by electrical stimuli of short duration. Propagation in one direction is blocked anodically by means of a quasi-trapezoidal stimulus wave form and a modified tripolar electrode configuration. Propagation in the other direction proceeds unhindered. This technique may be applicable to collision blocking of motor nerves for neural prostheses.