Articles

Calmodulin plays a pivotal role in cellular regulation

Science  04 Jan 1980:
Vol. 207, Issue 4426, pp. 19-27
DOI: 10.1126/science.6243188

Abstract

The role of calcium ions (Ca2+) in cell function is beginning to be unraveled at the molecular level as a result of recent research on calcium-binding proteins and particularly on calmodulin. These proteins interact reversibly with Ca2+ to form a protein . Ca2+ complex, whose activity is regulated by the cellular flux of Ca2+. Many of the effects of Ca2+ appear to be exerted through calmodulin-regulated enzymes.

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