Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence

See allHide authors and affiliations

Science  01 Feb 1980:
Vol. 207, Issue 4430, pp. 525-526
DOI: 10.1126/science.7352259


The purification of human fibroblast interferon has been simplified to a two-step procedure consisting of affinity chromatography on Blue Sepharose and sodium dodecyl sulfate polyacrlamide gel electrophoresis. A preliminary amino acid composition and the sequence of the 13 amino-terminal residues of homogeneous interferon prepared by this method is reported.