Postsynaptic transmission block can cause terminal sprouting of a motor nerve

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Science  08 Feb 1980:
Vol. 207, Issue 4431, pp. 649-651
DOI: 10.1126/science.6243417


Sprouting of mouse soleus motor nerve terminals can be evoked by daily intramuscular injections of purified alpha-bungarotoxin. This finding supports the hypothesis that an important stimulus to terminal sprouting in partial denervation and presynaptic nerve blockade is a product of inactive muscle fibers.