Parathyroid hormone: a coronary artery vasodilator

Science  07 Mar 1980:
Vol. 207, Issue 4435, pp. 1087-1089
DOI: 10.1126/science.7355275


Injection of synthetic bovine parathyroid hormone (the amino terminal peptide containing the first 34 amino acids) to the coronary circulation of the dog resulted in a marked coronary vasodilation. The vasodilatory response was dose-dependent and amounted to a 161 percent increase over the resting flow rate at a concentration of 1.0 unit per kilogram.