Prolongation of islet xenograft survival without continuous immunosuppression

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Science  11 Jul 1980:
Vol. 209, Issue 4453, pp. 283-285
DOI: 10.1126/science.6770465


The survival of isolated rat islets transplanted into diabetic mice was prolonged markedly by maintaining the rat islets in vitro at 24 degrees C for 7 days before transplantation and administering to the recipients a single injection of antiserum to mouse and rat lymphocytes shortly before transplantation.