Reports

C-Glucuronidation of the acetylenic moiety of ethchlorvynol in the rabbit

Science  08 Aug 1980:
Vol. 209, Issue 4457, pp. 703-704
DOI: 10.1126/science.7394528

Abstract

An acetylenic C-glucuronide of the sedative-hypnotic drug ethchlorvynol was isolated from rabbit urine as the major metabolite. The C-glucuronide represents a novel metabolic pathway for acetylenes and is a rare example of the formation of a carbon-glucuronide bond in mammalian systems.

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