2-Aminoethylphosphonic Acid Metabolism During Embryonic Development of the Planorbid Snail Helisoma

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Science  12 Sep 1980:
Vol. 209, Issue 4462, pp. 1245-1247
DOI: 10.1126/science.209.4462.1245


In freshly laid egg masses of Helisoma sp., more than 95 percent of the phosphorus is found in alkylphosphonic acids, as determined by phosphorus-31 nuclear magnetic resonance spectroscopy. These compounds are metabolized during embryonic development, as shown by differential acid hydrolysis and experiments with phosphorus-33-labeled phosphoric acid. Further, nuclear magnetic resonance spectroscopy indicates phosphonic acid involvement in related snail families, including the schistosomal vector Biomphalaria glabrata.