ArticlesEngineered Mutagenesis

Chemical DNA synthesis and recombinant DNA studies

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Science  19 Sep 1980:
Vol. 209, Issue 4463, pp. 1401-1405
DOI: 10.1126/science.6106285


Chemically synthesized DNA has been used in many recombinant DNA studies. These uses have included the total synthesis and cloning of functional genes, the cloning and expression of natural genes, and editing of changing genes by directed mutation.