Reports

Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster

See allHide authors and affiliations

Science  24 Oct 1980:
Vol. 210, Issue 4468, pp. 427-429
DOI: 10.1126/science.6776625

Abstract

When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of the breakpoints fall into a few highly localized positions on the chromosome. These positions are mostly at points of intercalary heterochromatin and may vary from one strain to the next. the results suggest that they may represent points of insertion of mobile DNA sequences.