Phosphorus distribution in the nucleosome

Science  09 Jan 1981:
Vol. 211, Issue 4478, pp. 169-170
DOI: 10.1126/science.7444457


The spatial distribution of phosphorus within active fraction nucleosomes reveals that the path of the DNA is consistent with one and three-fourths turns of DNA supercoiled around the outside of the protein core. This phosphorus distribution, obtained with an imaging electron spectrometer in a conventional transmission electron microscope, simultaneously establishes new limits of sensitivity for elemental microanalysis.