Assessment of pharmacological treatment of myocardial infarction by phosphorus-31 NMR with surface coils

Science  09 Jan 1981:
Vol. 211, Issue 4478, pp. 177-180
DOI: 10.1126/science.7444460


Phosphorus-31 nuclear magnetic resonance (NMR) measurements with small surface coils have been used to observe phosphorus metabolism of perfused hearts within localized regions. The method allows for direct, noninvasive, sequential assessment of the altered regional metabolism resulting from myocardial infarction and its response to drug treatment, which cannot be observed by conventional techniques.