Mutagenicity of fly ash particles in Paramecium

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Science  09 Jan 1981:
Vol. 211, Issue 4478, pp. 180-182
DOI: 10.1126/science.7444461

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Paramecium, a protozoan that ingests nonnutritive particulate matter, was used to determine the mutagenicity of fly ash. Heat treatment inactivated mutagens that require metabolic conversion to their active form but did not destroy all mutagenicity. Extraction of particles with hydrochloric acid, but not dimethyl sulfoxide, removed detectable mutagenic activity.