Electroretinographic responses to alternating gratings before and after section of the optic nerve

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Science  27 Feb 1981:
Vol. 211, Issue 4485, pp. 953-955
DOI: 10.1126/science.7466369


Electroretinographic (ERG) responses to sinusoidal gratings reversed in contrast (pattern-reversal ERG) were recorded from both eyes of cats before and after unilateral section of the optic nerve. In the eye ipsilateral to the section, the pattern-reversal ERG remained unaltered for a few days after the section, the progressively decreased in amplitude, first at low and then at high spatial frequencies, to disappear completely about 4 months after the section, when ganglion cell degeneration was practically complete. The flash ERG remained unaltered. No alteration was observed in the contralateral eye.