Mammalian gonadal determination and gametogenesis

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Science  20 Mar 1981:
Vol. 211, Issue 4488, pp. 1265-1271
DOI: 10.1126/science.6259727


Although a relationship between the X and Y chromosomes and mammalian sexual development has long been recognized, a detailed understanding of this relation is still lacking. Recent advances in somatic cell genetics and recombinant DNA technology should provide the tools for solving this fundamental problem in developmental genetics.