Aerial spraying of 2,4,5-T and human birth malformations: an epidemiological investigation

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Science  17 Apr 1981:
Vol. 212, Issue 4492, pp. 349-351
DOI: 10.1126/science.7209535


An investigation of the rate of birth malformations in the Northland region of New Zealand provides no evidence to associate spraying of 2,4,5-trichlorophenoxyacetic acid with the occurrence of any malformation of the central nervous system, including spina bifida. A statistically significant association between spray and malformation is found in the case of talipes. Whether this association indicates a causal relation remains to be established.