Reports

Cross-contamination of cells in culture

Science  24 Apr 1981:
Vol. 212, Issue 4493, pp. 446-452
DOI: 10.1126/science.6451928

Abstract

Lists are presented of references to all known publications describing cell properties that serve to characterize (i) known strains of HeLa and purported human cell lines indicated as HeLa contaminants, (ii) strains of human cell lines contaminated with human but non-HeLa cells, and (iii) strains of cells contaminated by cells from one or more other species. Frequencies of cell cross-contaminations are cited and references are presented to relatively simple techniques that could serve to detect such contamination.

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