Tyrosine increases blood pressure in hypotensive rats

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Science  01 May 1981:
Vol. 212, Issue 4494, pp. 559-560
DOI: 10.1126/science.7209553


Administration of tyrosine, the amino acid precursor of catecholamines, increased blood pressure 38 to 49 percent in rats made acutely hypotensive by hemorrhage; other large neutral amino acids were ineffective. Tyrosine's effect was abolished by adrenalectomy, suggesting that, in hypotensive animals, it acts by accelerating the peripheral synthesis and release of catecholamines.

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