Rod-cone interaction in the distal human retina

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Science  15 May 1981:
Vol. 212, Issue 4496, pp. 829-831
DOI: 10.1126/science.7221568


During the rod-isolated phase of dark adaption, b-wave implicit time of the human cone electroretinogram increased exponentially with a time constant corresponding to that for the regeneration of rhodopsin. In the presence of different photopically equated short-wave backgrounds, cone b-wave implicit time varied inversely with the scotopic brightness of the background. Taking into account the origin of the b wave, these measurements support the idea of a rod effect on cone function in the distal human retina.