Rapid forgetting of a spatial habit in rats with hippocampal lesions

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Science  22 May 1981:
Vol. 212, Issue 4497, pp. 959-960
DOI: 10.1126/science.6785882


Rats with lesions of the hippocampus or mammillary bodies were impaired in learning reversal problems in a T-maze. Test trials given after learning each reversal disclosed little forgetting in the mammillary body group but rapid forgetting in the hippocampal group. These findings resemble those recently reported in patients with amnestic syndromes.