Somatic cell hybrids from frog lymphocytes and mouse myeloma cells

Science  29 May 1981:
Vol. 212, Issue 4498, pp. 1034-1035
DOI: 10.1126/science.6785884


Stable somatic cell hybrids were obtained by fusing Xenopus lymphocytes with mouse myeloma cells. These hybrids contained one to four Xenopus chromosomes and expressed Xenopus gene products, one of which was a lymphocyte membrane protein of 85,000 daltons precipitated by a monoclonal antibody.