Reports

Contractility of bile canaliculi: implications for liver function

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Science  29 May 1981:
Vol. 212, Issue 4498, pp. 1041-1042
DOI: 10.1126/science.7015506

Abstract

Dynamic contractions of bile canaliculi were observed in groups of cultured hepatocytes by time-lapse cinephotomicrography during the early stages of monolayer formation. The contractions, which were forceful and appeared to have a pumping action, may facilitate the flow of bile in the liver's canalicular system.