Chemical modification of carotid body chemoreception by sulfhydryls

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Science  29 May 1981:
Vol. 212, Issue 4498, pp. 1065-1066
DOI: 10.1126/science.6262913


Sulfhydryl reagents cause striking augmentation of the chemoreceptor responses of the carotid body to hypoxia. This indicates that a cellular plasma membrane protein with a reactive sulfhydryl group is a constituent part of the chemoreceptor architecture and provides a means of identification, localization, and isolation of the protein.