Serum albumin beads: an injectable, biodegradable system for the sustained release of drugs

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Science  10 Jul 1981:
Vol. 213, Issue 4504, pp. 233-235
DOI: 10.1126/science.6787705


Biologically active compounds were entrapped in cross-linked serum albumin microbeads. Injection of these drug-impregnated beads into rabbits produced no adverse immunological reactions. Sustained release (20 days) of progesterone was demonstrated in vivo.