Circadian rhythms of blood minerals in humans

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Science  07 Aug 1981:
Vol. 213, Issue 4508, pp. 672-674
DOI: 10.1126/science.7256269


Circadian rhythms of ionized calcium and phosphate concentrations have been demonstrated in human blood. A computer-derived model curve representing the 24-hour fluctuations in ionized calcium cannot be correlated consistently with curves for total calcium or phosphate. Knowledge of these circadian rhythms provides a physiological basis for further understanding the interactions between blood minerals and calcium-regulating hormones.