Range of radiochemical damage to DNA with decay of iodine-125

Science  21 Aug 1981:
Vol. 213, Issue 4510, pp. 896-898
DOI: 10.1126/science.7256283


Studies of the length of DNA fragments produced upon decay of iodine-125-labeled deoxycytidine that was located at a single position within a DNA fragment of defined sequence demonstrate that most radiochemical damage occurs within 15 to 20 angstroms of the site of iodine-125 decay. However, DNA strand breakage was detectable up to 70 angstroms from the site of iodine-125 decay.