Differentiation of respiratory and abortigenic isolates of equine herpesvirus 1 by restriction endonucleases

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Science  30 Oct 1981:
Vol. 214, Issue 4520, pp. 562-564
DOI: 10.1126/science.6270790


Viruses classified by immunologic criteria as equine herpesvirus 1 cause respiratory disease and abortion in horses. Restriction endonuclease analyses of the DNA's of viruses from animals with respiratory disease and from aborted fetuses show that the patterns for respiratory viruses, while similar to each other, are entirely different from the patterns for fetal viruses. It is therefore proposed that the DNA restriction endonuclease patterns of fetal and respiratory viruses analyzed in this study be designated as prototypic of equine herpesvirus 1 and 4, respectively.