Correcting the phenotype of the epidermis from chick embryos homozygous for the gene scaleless (sc/sc)

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Science  27 Nov 1981:
Vol. 214, Issue 4524, pp. 1033-1034
DOI: 10.1126/science.7029712


Scutate scales are completely missing in the scaleless (sc/sc) mutant chicken. Organ cultures consisting of epidermis from sc/sc embryos combined with normal (+/+) scale dermis of the same developmental age produce the scaleless phenotype, but the same scaleless epidermis in combination with normal dermis from more differentiated embryonic scales forms perfectly normal scales.