Actin distribution patterns in the mouse neural tube during neurulation

Science  08 Jan 1982:
Vol. 215, Issue 4529, pp. 172-174
DOI: 10.1126/science.7031898


With the use of antibodies to actin and indirect immunofluorescent techniques regions of increased actin concentration were demonstrated first in basal and later in apical areas of mouse neuroepithelial cells. These patterns of staining corresponded to shape changes observed in cranial neural folds as they initially elevated from the neural plate and later moved toward the midline.