Queuine, a modified base incorporated posttranscriptionally into eukaryotic transfer RNA: wide distribution in nature

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Science  02 Apr 1982:
Vol. 216, Issue 4541, pp. 55-56
DOI: 10.1126/science.7063869


Queuine, a modified base found in transfer RNA, appears to be a new dietary factor because (i) previous studies have shown that mice require it for the expression of queuine-containing transfer RNA's but apparently do not synthesize it, and (ii) significant amounts of free queuine are present in common plant and animal food products.