Reports

Heroin "overdose" death: contribution of drug-associated environmental cues

Science  23 Apr 1982:
Vol. 216, Issue 4544, pp. 436-437
DOI: 10.1126/science.7200260

Abstract

A model of "overdose" deaths among heroin addicts is proposed which emphasizes recent findings concerning the contribution of drug-associated environmental cues to drug tolerance. Results of animal experiments performed to evaluate this model suggest that conditioned drug-anticipatory responses, in addition to pharmacological factors, affect heroin-induced mortality.

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