Sodium transport inhibition by amiloride reduces basolateral membrane potassium conductance in tight epithelia

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Science  30 Apr 1982:
Vol. 216, Issue 4545, pp. 525-527
DOI: 10.1126/science.7071599


In toad and frog urinary bladder, electrophysiological data suggest that inhibition of transepithelial sodium transport by mucosal amiloride results in a decrease in basolateral membrane conductance. These results were confirmed by showing that amiloride addition caused a decrease in basolateral membrane potassium permeability.