Calcium ionophore polarizes ooplasmic segregation in ascidian eggs

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Science  30 Apr 1982:
Vol. 216, Issue 4545, pp. 545-547
DOI: 10.1126/science.6803360


Calcium ionophore A23187 promotes ooplasmic segregation and orange crescent formation in eggs of the ascidian Boltenia villosa. When eggs were exposed to a gradient A23187 the orange crescent was induced to form in the region corresponding to the highest concentration of ionophore. This result is consistent with the hypothesis that a local increase in intracellular calcium polarizes cytoplasmic localization in the ascidian embryo.