Histocompatibility and isoenzyme differences in commercially supplied "BALB/c" mice

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Science  23 Jul 1982:
Vol. 217, Issue 4557, pp. 379-381
DOI: 10.1126/science.6953593


BALB/c mice obtained commercially were found to differ significantly from the standard phenotype of BALB/c strain mice. Isoenzyme tests and H-2 haplotype analyses indicated that the majority of mice from two of the three sources tested appeared mixed, frequently heterozygous, and did not consistently express either the expected H-2 or glucose phosphate isomerase type.