Cysteamine: a potent and specific depletor of pituitary prolactin

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Science  30 Jul 1982:
Vol. 217, Issue 4558, pp. 452-454
DOI: 10.1126/science.7089575


Cysteamine rapidly reduces the concentration of prolactin in pituitary tissue in vivo and in vitro. The effect is dose-dependent, reversible, and cannot be accounted for by prolactin release. Cysteamine does not appear to exert its effect through dopamine receptors and does not alter lactotrope morphology, as determined by electron microscopy.