Mucus secretion-stimulating activity in human lymphoblastoid cells

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Science  20 Aug 1982:
Vol. 217, Issue 4561, pp. 736-737
DOI: 10.1126/science.6285469


Two fractions isolated from cultured lymphoblastoid cells stimulated mucus secretion from the urn cell complex of the marine invertebrate Sipunculus nudus. The activity detected in the nuclear fraction was trypsin-sensitive, and it increased in response to specific nucleotides.