Liquid Chromatography in 1982

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Science  15 Oct 1982:
Vol. 218, Issue 4569, pp. 235-241
DOI: 10.1126/science.218.4569.235


Classical liquid chromatography gave rise 15 years ago to new ideas about high-speed separations. Today, difficult separations can be made almost routinely by use of liquid chromatography instruments with automated controls and sensitive detectors. Sorptive effects are often best achieved with small, porous, "bonded phase" particles. The trend is to control the chemical selectivity by means of the liquid phase. These techniques are easily learned, and they have been widely accepted throughout chemistry and its allied disciplines. As a result, liquid chromatography has become the most rapidly expanding branch of the chemical instrumentation field.