Sugar infusion can enhance feeding

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Science  29 Oct 1982:
Vol. 218, Issue 4571, pp. 490-491
DOI: 10.1126/science.7123251


An investigation was made of the role of glucose in the regulation of hunger and satiety in the rabbit. Glucose, when infused intraduodenally at a low rate (1 milliliter per minute), produced a decrease in food intake. However, when glucose was infused into the duodenum at a high rate (3 milliliters per minute), the rabbits nearly doubled their food intake during the first half-hour after infusion. It is hypothesized that the rapid arrival and glucose in the duodenum may produce hunger.