Crown Gall Disease and Prospects for Genetic Manipulation of Plants

Science  26 Nov 1982:
Vol. 218, Issue 4575, pp. 854-859
DOI: 10.1126/science.218.4575.854


Agrobacterium tumefaciens incites crown gall tumors when bacterial DNA integrates into plant nuclear DNA. Plant cells can express these integrated bacterial genes. Following insertion of desired genes into bacterial DNA using recombinant DNA techniques, this system permits introduction of these new genes into plant DNA. We discuss the potential for genetic manipulation of plants using Agrobacterium tumefaciens and the related organism Agrobacterium rhizogenes.