Neuromagnetic localization of epileptiform spike activity in the human brain

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Science  26 Nov 1982:
Vol. 218, Issue 4575, pp. 891-894
DOI: 10.1126/science.6813968


Local paroxysmal discharges of epileptic tissue within the human brain, which may be electrically recorded as voltage spikes in the electroencephalogram, also generate extracranial magnetic fields. These fields were assessed by means of recently developed neuromagnetometric techniques. Surface measurements of magnetic spike field strength in the region of the focus appear sufficient to establish the location, depth, orientation, and polarity of currents underlying the paroxysmal discharge.